Very interesting that you should mention PTOY. I know them pretty well. They're one of the very first movers in the patient oriented blockchain healthcare platforms. I think they have some good ideas and given the first mover advantages I can see them being able to grow their valuation even further for a little while. However, the patient oriented blockchain business model is definitely a challenge to execute at scale for some time to come. There are lots of reasons for that, not least though the very large number of stakeholders in the mix, many of whom (think insurers vs. patients) don't necessarily want transparency or disintermediation.
I think PTOY will do well independently at least for a while, with possible acquisition by a larger player (someone already with cloud EHR software, like Athena) in the mid-term.