By a News Reporter-Staff News Editor at Cannabis & Marijuana News -- Research findings on Marijuana/Cannabis - Marijuana Usage are discussed in a new report. According to news reporting from Wollongong, Australia, by NewsRx journalists, research stated, “Chronic cannabis use has been associated with impaired cognition and elevated psychological symptoms, particularly psychotic-like experiences. While D-tetrahydrocannabinol (THC) is thought to be primarily responsible for these deleterious effects, cannabidiol (CBD) is purported to have antipsychotic properties and to ameliorate cognitive, symptomatic, and brain harms in cannabis users.”
The news correspondents obtained a quote from the research from the University of Wollongong, “However, this has never been tested in a prolonged administration trial in otherwise healthy cannabis users. Here, we report the first study of prolonged CBD administration to a community sample of regular cannabis users in a pragmatic trial investigating potential restorative effects of CBD on psychological symptoms and cognition. Twenty frequent cannabis users (16 male, median age 25 years) underwent a 10-week open-label trial of 200 mg of daily oral CBD treatment, while continuing to use cannabis as usual. The majority of participants were daily cannabis users who had used cannabis for several years (median 5.5 years of regular use). Participants underwent psychological and cognitive assessments at baseline (BL) and post-treatment (PT) and were monitored weekly throughout the trial. CBD was well tolerated with no reported side effects; however, participants retrospectively reported reduced euphoria when smoking cannabis. No impairments to cognition were found, nor were there deleterious effects on psychological function. Importantly, participants reported significantly fewer depressive and psychotic-like symptoms at PT relative to BL, and exhibited improvements in attentional switching, verbal learning, and memory. Increased plasma CBD concentrations were associated with improvements in attentional control and beneficial changes in psychological symptoms. Greater benefits were observed in dependent than in nondependent cannabis users. Prolonged CBD treatment appears to have promising therapeutic effects for improving psychological symptoms and cognition in regular cannabis users.”
According to the news reporters, the research concluded: “Our findings require replication given the lack of a placebo control in this pragmatic trial, but suggest that CBD may be a useful adjunct treatment for cannabis dependence.”
For more information on this research see: Therapeutic Effects of Prolonged Cannabidiol Treatment on Psychological Symptoms and Cognitive Function in Regular Cannabis Users: A Pragmatic Open-Label Clinical Trial. Cannabis and Cannabinoid Research , 2018;3(1):21-34.
Our news journalists report that additional information may be obtained by contacting N. Solowij, School of Psychology and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, Australia. Additional authors for this research include S.J. Broyd, C. Beale, J.A. Prick, L.M. Greenwood, H. van Hell, C. Suo, P. Galettis, N. Pai, S. Fu, R.J. Croft, J.H. Martin and M. Yucel.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1089/can.2017.0043. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
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CITATION: (2018-04-17), Study Results from University of Wollongong Provide New Insights into Marijuana Usage (Therapeutic Effects of Prolonged Cannabidiol Treatment on Psychological Symptoms and Cognitive Function in Regular Cannabis Users: A Pragmatic Open-Label ...), Cannabis & Marijuana News, 50, ISSN: 0000-0000, BUTTER® ID: 015492380
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