Calcineurin inhibitors (CNIs) belong to the class of medications called immunosuppressants. They are used in the management of autoimmune conditions and are mainstays for immunosuppression in solid organ transplants.
The two most commonly used calcineurin inhibitors are: Cyclosporine and Tacrolimus
Tacrolimus (also known as FK506) is another calcineurin inhibitor used primarily in organ transplantation. It is considered an alternative to cyclosporine and is often used when cyclosporine is not well-tolerated or is ineffective. Calcineurin inhibitors and their uses and applications