Very few Americans are immunologically naïve against SARS-COV-2 at this point. This is why the FDA has simplified the vaccination guidance to a single bivalent primary series dose for unvaccinated adults.
For those that are unvaccinated, hybrid immunity has been demonstrably superior. So if you know someone that is still unvaccinated, even if they have been previously infected, try to convince them to get the bivalent vaccine. Once the CDC signs off on the new guidance they will only need to get one primary series dose.
There are definitely people that have not been infected yet, so it certainly is possible. Though relatively speaking it is mostly older adults that haven't been infected.
By age:
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