New: tumorcell

oajbs (27)in oajbs • 2 years ago
Tumor Cells are Vitally Dependent upon Ketolysis, Inhibition of Succinyl CoA: 3-Oxoacid-CoA Transferase Should Block Them
In tumor cells, ketolysis becomes the unique source of mitochondrial acetyl CoA. Indeed, the glycolytic acetyl CoA production is blocked (pyruvate kinase and pyruvate dehydrogenase are inhibited by…
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Tumor Cells are Vitally Dependent upon Ketolysis, Inhibition of Succinyl CoA: 3-Oxoacid-CoA Transferase Should Block Them