PRESENTATION
Genomequity plans to make a community oriented stage that rewards clients for sharing their DNA with analysts. We will likely set up one of the world's biggest accumulations of hereditarydata. Direct to Customer Hereditary Testing Direct to shopper hereditary testing is an expansive and developing business sector, expected to develop from $70.2M in 2015 to $340M in 2022 [1]. Organizations including 23andMe and Ancestry.com, command this developing business sector, moving DNA gathering units and DNA examination benefits specifically to customers for around $100-$200 per test. Purchasers send in their DNA to these organizations and thus get customized reports containing data about their hereditary qualities, wellbeing, conduct, parentage, and transporter status for some inheritable hereditary infections.
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The messy mystery behind these organizations is that they pitch their client's hereditary data to huge pharmaceutical organizations for many dollars. In 2015, 23andMe made an arrangement with Genentech and sold access to their client information for $60 million [2]. The organization allegedly has extra arrangements set up with Pfizer and numerous other medication organizations and research establishments. Lamentably, singular clients are not remunerated at all for the closeout of their own hereditary data, as unveiled somewhere down in 23andMe's terms of administration understanding:
You comprehend that you ought not expect any monetary profit by 23andMe as a consequence of having your Hereditary Data handled; made accessible to you; or, as given in our Security Proclamation and Terms of Administration, imparted to or incorporated into
Collected Hereditary and Self-Announced Data imparted to look into accomplices, counting business accomplices.
More terrible, regardless of whether you explicitly quit 23andMe's examination program and don't agree to the organization utilizing your individual dimension information, 23andMe still offers your information in collected shape with outsiders [4]. What's more, purchasers get hit again by paying over the top costs for pharmaceutical items sold by similar organizations that utilization their own hereditary data as a component of their medication Research and development endeavors. We trust that the individual clients of these stages are the legitimate proprietors of their hereditary data and have the right to be redressed and educated if their hereditary data is being sold.
VISION
Our vision is to make a stage that enables clients to get remuneration for sharing their DNA with specialists. Clients contribute hereditary data by submitting physical examples and by providing supplemental individual data through supported studies. Singular clients' hereditary data can be anonymized and collected to make a huge, powerful database of hereditary data that can be shared or sold to scientists. We intend to assemble an open stage, where outsider engineers and specialist organizations can assemble applications and pitch extra administrations to clients, including extra DNA examination and hereditary advising. Contributing clients' DNA tests will just should be physically prepared one time, and after that can be carefully put away, looked, dissected, and questioned various occasions, subsequently bringing down the expense of test procurement and investigation for analysts and taking into consideration open doors for clients to consistently increase new bits of knowledge from their DNA with only one physical test.
ABOUT THE GENOMEQUITY STAGE
The Genomequity stage associates clients, scientists, and specialist organizations to share and move hereditary data and administrations. The jobs of the majority of the members in the Genomequity biological community are point by point beneath:
Genomequity keeps up the database of hereditary data. The organization moves DNA accumulation units and hereditary reports to clients, and pitches access to the hereditary data database to scientists. Genomequity additionally charges an expense to outsiders that move applications and administrations on the stage.
#USERS
Clients buy DNA gathering packs from Genomequity, and send in their DNA tests for preparing. Thusly, they get hereditary reports and get access to a computerized DNA profile in the framework. Clients may take an interest in online research considers supported by specialists and get remuneration for sharing extra information. Clients may likewise impart their hereditary profile to outsider specialist organizations and buy extra tests or administrations from them.
Pharmaceutical organizations, scholarly specialists, and biotech organizations pay expenses to access and hunt the database of hereditary data. They may likewise pay expenses to support custom studies offered to the client base. A bit of these charges might be given to clients as a motivating force to take part in the reviews and persistently enhance the database.
#SERVICE SUPPLIERS
Specialist organizations pitch hereditary tests and administrations to clients. Clients allow these suppliers access to their put away advanced DNA profiles, and these suppliers play out extra examination on the put away dataset.
Outsider research centers give the administrations important to remove, filter, and break down client DNA tests. Physical DNA tests from the gathering packs are sent to outside labs, and the research centers furnish Genomequity with the examination results. Physical examples are then sent to outsider biobanks.
Outsider biobanks keep up leftover examples for long haul solidified capacity. The examples may later be utilized in extra examinations, or sold to specialists.
DNA investigation There are a few strategies for breaking down DNA that might be utilized by Genomequity or its third party specialist co-ops.
SNP GENOTYPING
Genotyping is the most savvy approach for genome-wide affiliation contemplates, and is ordinarily utilized by many direct to buyer genomics organizations. The innovation regularly utilizes DNA microarrays to test for known varieties in human DNA, known as single nucleotide polymorphisms or SNPs. Units accessible today can test from between 300,000 to more than 5 million known variations and are evaluated in the scope of $100-500 for each example.
DIRECTED QUALITY BOARDS
Directed quality sequencing boards are valuable when seeing explicit conditions, for example, deciding malignant growth hazard or testing for hereditary sickness bearer status for family arranging. These tests commonly succession few qualities to identify for the nearness of realized groupings connected to different illnesses. Quality boards cost around $250 and up. Exome Sequencing Exome sequencing innovation arrangements the whole protein coding area of the human genome, roughly 1.5% of the genome comparing to around 20,000 qualities. This approach is a productive method to recognize hereditary variations found in protein successions at a much lower cost than entire genome sequencing. Exome sequencing costs roughly $500-1,000 for every example.
ENTIRE GENOME SEQUENCING
Entire genome sequencing breaks down each and every base combine of DNA in the human genome, around 3 billion base sets. In spite of the fact that costs have descended altogether throughout the decade, it is still restrictively costly to lead this sort of examination over a populace scale test estimate. Notwithstanding the expense for getting ready and sequencing the genome, there are huge costs required with breaking down and putting away such a substantial informational index. Normal costs today for entire genome sequencing begin at around $1,000 and up.
GENOMEQUITY TOKEN (GEQ)
Every single inside exchange inside the Genomequity stage are directed utilizing Genomequity utility tokens, which can be best idea of as tradable programming access rights. We imagine numerous utilizations for the token on the Genomequity stage.
For analysts:
Access rights to seek and download information from the hereditary database.
Access rights to make and direct custom overviews on the stage.
For application engineers and specialist organizations:
Access rights to move benefits on the stage.
For clients:
- Access rights to utilize benefits on the stage. In our financial model, clients may win tokens for submitting tests to the stage and for taking an interest in supported research examines. Clients may then utilize those tokens to buy DNA examination administrations from Genomequity or its outsider specialist co-ops. Scientists may pay to get to the hereditary database and may offer motivating forces to clients for their investment in supported studies. Application designers and specialist organizations may pay for the privilege to list their administrations on the stage. Genomequity, as the stage administrator, may charge little expense on all exchanges inside the framework.
TOKENS DETAILS
We intend to support the improvement of our stage through an open token clearance of Genomequity utility tokens. We intend to raise at least $2M, up to a hard top of $20M.
Token subtleties are as per the following:
Absolute token supply: 100,000,000
Open offering: 30,000,000
Genomequity Store: 60,000,000
Group: 10,000,000
Tokens saved for general society deal might be sold by Genomequity on the open market through the Waves Decentralized Trade or sold in private deal occasions at the sole tact of Genomequity. Tokens held for the Genomequity Reserve are controlled by Genomequity and are planned to be utilized as a pool of motivation tokens to be occasionally paid out to clients and early adopters of the stage after some time. In the event that our financing is effective, we intend to utilize our assets as point by point beneath:
A substantial part of assets will be utilized to build up the framework for our hereditary database frameworks, to build up our hereditary testing reports, and to create wallets and foundation to deal with the GEQ tokens.
#DNA EXAMINATION
A noteworthy part of assets will be utilized to build up our custom DNA accumulation units and to give free DNA packs and investigation to early adopters to manufacture our alpha database.
#LEGAL/ADMINISTRATIVE
We hope to spend a lot of assets on lawful and administrative administrations to guarantee that we are agreeable with every single pertinent control in the wards we expect to work in.
Assets saved for promoting purposes will be utilized to pull in clients, partners,researchers, designers, and specialist organizations expected to assemble our locale.
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