Global Gene Synthesis Industry: Key Statistics and Insights in 2025-2033
Summary:
- The global gene synthesis market size reached USD 2.4 Billion in 2024.
- The market is expected to reach USD 9.6 Billion by 2033, exhibiting a growth rate (CAGR) of 15.75% during 2025-2033.
- North America leads the market, accounting for the largest gene synthesis market share.
- Solid-phase synthesis accounts for the majority of the market share in the method segment due to its high efficiency and scalability, allowing for rapid, accurate production of complex gene sequences.
- Antibody DNA synthesis holds the largest share in the gene synthesis industry.
- Gene and cell therapy development represents the leading application segment.
- Academic and government research institutes remain a dominant segment in the market.
- The increasing use of gene synthesis in research, drug discovery, and biotechnology is a primary driver of the gene synthesis market.
- The rise of clustered, regularly interspaced short palindromic repeats (CRISPR) and other gene-editing technologies is e reshaping the gene synthesis market.
Industry Trends and Drivers:
- Expanding Applications in Research and Biotechnology:
The rising demand of gene synthesis in the study, in drug development as well as in biotechnology is driving the market advancement. Scientists utilize gene synthesis to construct precise genetic content for research on disease modes, design genetic therapies, and design desired genetically modified organisms. This customization capability increases the rate of research since scientists can study at molecular level various biological processes which they would otherwise have to use DNA isolation to get. In biotechnology, gene synthesis can produce enzymes, proteins, and bioengineered products in volumes that are relevant to the industrial market, thus used widely in areas such as biofuel, pharmaceuticals, and agricultural applications. While synthetic gene services are on the rise due to laboratories and biotech firms’ rising investments in these fields, technological developments that take costs down and enhance accuracy are advancing.
- Advancements in CRISPR and Gene Editing Technologies:
This is because clustered, regularly interspaced short palindromic repeats (CRISPR) and the other gene editing technologies require synthetic genes as key reagents in the entire gene editing process. Companies involved in the synthesis of genes offer carefully designed oligonucleotides that serve as a substrate for CRISPR changes. Such support enhances ease of genome editing projects, as they can be achieved at scales and with precision that was hitherto practically impossible. In addition, as the spectrum of the application of CRISPR broadens from direct correction of genetic diseases to improvement of agricultural traits, synthetic genes are used for experiments, as well as for interstudy reproducibility. The combined application of gene synthesis and gene-editing technology has been found to push the growth of the market.
- Growing Demand for Personalized Medicine and Synthetic Biology:
Personalized medicine and synthetic biology are reshaping healthcare. They are driving up the need for gene synthesis. Personalized medicine customizes treatments based on genetic profiles. This often requires creating specific genes or DNA for study. Meanwhile, synthetic biology involves designing organisms for specific tasks. For example, some bacteria are engineered to break down pollutants or make biofuels. Gene synthesis is crucial here. It allows for the creation of precise DNA needed in these projects. As interest in personalized medicine and synthetic biology grows, so does the demand for adaptable and accurate gene synthesis. This trend pushes providers to improve their methods.
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Gene Synthesis Market Report Segmentation:
Breakup By Method:
- Solid-Phase Synthesis
- Chip-Based Synthesis
- PCR-Based Enzyme Synthesis
Solid-phase synthesis represents the largest segment due to its high efficiency and scalability, allowing for rapid, accurate production of complex gene sequences.
Breakup By Services:
- Antibody DNA Synthesis
- Viral DNA Synthesis
- Others
Antibody DNA synthesis holds the biggest market share because of the growing need for custom antibodies in medical research, diagnostics, and therapeutic development.
Breakup By Application:
- Gene and Cell Therapy Development
- Vaccine Development
- Disease Diagnosis
- Others
Gene and cell therapy development account for the majority of the market share, driven by the increasing focus on genetic treatments for complex diseases.
Breakup By End Use:
- Biotechnology and Pharmaceutical Companies
- Academic and Government Research Institutes
- Contract Research Organizations
Academic and government research institutes represent the leading segment as they drive foundational research and development across various gene synthesis applications.
Breakup By Region:
- North America (United States, Canada)
- Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, Others)
- Europe (Germany, France, United Kingdom, Italy, Spain, Russia, Others)
- Latin America (Brazil, Mexico, Others)
- Middle East and Africa
North America enjoys the leading position attributed to its extensive government funding, advanced biotechnology infrastructure, and a strong focus on healthcare innovation.
Top Gene Synthesis Market Leaders:
The gene synthesis market research report outlines a detailed analysis of the competitive landscape, offering in-depth profiles of major companies. Some of the key players in the market are:
- ATUM
- Boster Biological Technology
- Eurofins Genomics
- Genewiz Inc. (Azenta Life Sciences)
- Genscript Biotech Corp.
- Integrated DNA Technologies Inc.
- Merck KGaA
- OriGene Technologies Inc.
- ProMab Biotechnologies Inc.
- ProteoGenix Inc
- Thermo Fisher Scientific Inc.
- Twist Bioscience
Note: If you require any specific information that is not covered currently within the scope of the report, we will provide the same as a part of the customization.
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