Phenibut (β-Phenyl-γ-aminobutyric acid )is central nervous system depressant marketed as a nootropic or brain enhancing chemical. Phenibut is a closely related structural analog of the naturally occurring neurotransmitter γ-aminobutyric acid (GABA). It was developed in the soviet union in the 1960s and is prescribed for PTSD, anxiety, depression, insomnia, studdering and other various conditions. In the United States, the chemical is neither approved or scheduled so that it can be sold as a nutritional supplement. Its nootropic functions include anxiety reduction, increased focus, and mood lift. It is classified as an anxiolytic.
Physical Effects:
- Stimulation and Sedation – At lower doses, phenibut has a mild physical and mental stimulation effect, encouraging movement, wakefulness, and productivity. At higher doses, however, it becomes physically sedating, promoting sleep and lethargy. Sleeping after dosing a small amount results in a deep, restful sleep which can leave the user feeling refreshed and alert upon waking.
- Respiratory depression
- Nausea – Phenibut can induce mild to extreme nausea depending greatly on dose and tolerance. It usually manifests roughly 5 hours after the initial dose and generally involves waves of nausea accompanied by vomiting and excessive sweating.
- Increased perspiration
- Motor control loss
- Physical euphoria
- Increased libido
- Orgasm suppression – At higher doses, rather than reducing sensitivity, phenibut has a propensity to cause spontaneous motor control loss when nearing orgasm.
- Stomach cramps
- Dizziness
- Dehydration – Dehydration is reported to occur from regular multi-day usage or overdoses.
- Headaches – Moderate to high doses can induce a mild headache many hours after dosing.
- Muscle cramps – Muscle cramps and joint pain are sometimes accompanied at high doses.
- Difficulty urinating – This effect generally only occurs after frequent usage.
- Increased blood pressure
- Temperature regulation loss
- Appetite enhancement
Cognitive Effects:
- Anxiety suppression
- Disinhibition
- Cognitive euphoria
- Empathy, affection, and sociability enhancement- Phenibut has been reported to produce strong prosocial and entactogenic effects which, although much weaker than that of traditional entactogens such as MDMA, are still prominent and well-defined even at light to conventional doses.
- Information processing suppression- High doses will usually induce a state of mild stupor and confusion.
- Thought deceleration
- Motivation enhancement
- Increased music appreciation
- Compulsive redosing
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