The end of cancer is very near
What is Dostarlimab?
It belongs to the category of immunotherapies; It works by inhibiting the PD-1 channel, which controls the body's immune response to cancerous tumors.
It is also a monoclonal antibody, and was initially used to treat endometrial cancer, and then clinical trials expanded to find its potential in treating other cancerous tumors.
This medicine was released under the name Jimperli, and it is in the form of a clear liquid injected into a vein.
It also works to enhance immunity, so the body can kill cancer cells, without the drug attacking the tumor itself.
Indications for use of Dustarlimab injection
Indications for use of Gembrilli include:
• Treatment of endometrial cancer in addition to the treatment of certain types of solid cancerous tumors.
• Treatment of colon cancer; The doctors noticed promising and amazing results on patients.
Gembrilli's mechanism of action
Monoclonal antibodies are synthetic antibodies that researchers have prepared in laboratories to fight certain diseases.
Dustarlimab is designed to block a protein (PD-1) found in cancer cells, so the cancer cells metastasize to the immune system, and are easier to identify and destroy.
How to use dostarlimab
This drug is taken for the first four doses by intravenous infusion for 30 minutes every three weeks, then every six weeks starting with the fifth dose.
Dostarlimab contraindications
In the beginning, it is necessary to follow up and diagnose the patient's condition well before using this drug; It is prohibited to take it in the following cases:
• Breathing problems.
• Immune disorders.
Dustarlimab side effects
Despite the amazing benefits of Gembrilli, it may cause some side effects, such as:
• Bloody diarrhea.
• Sores of the throat and tongue.
• Severe stomach pain.
• Anorexia.
• Excessive thirst.
• Obesity.
• Bleeding.
• Feeling unbearable cold or heat.
• People with liver disease may experience yellowing of the eyes, nausea and dark urine.
• Change the color of the urine to pink blood and its quantity in case of kidney problems.
• Arrhythmia.
• Hard breathing.
• Mood swings.
• Cramps.
• The sensitivity of the eye to light.
Is dostarlimb 100% safe?
Unfortunately, the answer is no, it is still under research and experiment, and it is also possible that severe immune reactions may occur that may lead to death.
This drug may also cause 1.4% of autoimmune pneumonia, which is fatal if the patient has received chest radiation before.
It can also cause some serious consequences, such as:
• Immune nephritis by 0.4%.
• Type 1 diabetes mellitus.
• Thyroid disorders.
• Adrenal insufficiency at a rate of 1.4%.
• Hepatitis immune by 0.2%.
• Incidence of immune colitis at a rate of 1.4%.
• Fetal malformation.
• Skin rash.
Dostarlimab injection price
The price of a single injection of Dostarlimab is estimated at $11,000, and accordingly it can be said that the cost of the full treatment with the drug can reach $88,000 or more depending on the number of doses, which is a high price.
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