Tourism businesses in Cornwall fear they will "run out of money" because of measures to curb the spread of coronavirus.
A hotel owner said a lockdown to fight the pandemic had come at the "worst possible" time for traders.
Businesses joined politicians in urging travellers to stay away to help the NHS cope with Covid-19.
However the government-enforced lockdown means some will lose most of their income for the year.
Kim Conchie from Cornwall Chamber of Commerce said there was "no way" some businesses would survive the summer.