All I know is that he was depressed or perhaps suffering from a physical illness. I searched online and found this:

The philosopher’s lack of success — he became famous only after his death — and lack of social contact also caused him stress. “It hurts me frightfully that in these fifteen years not one single person has ‘discovered’ me, has needed me, has loved me,” a letter reads. “How rarely a friendly voice reaches me!” another adds. “I’m now alone, absurdly alone.”

It seems that those with great minds often suffer from depression...I guess I'd better become a mad hatter then 😅 Oh! And Bartolino! I envy him. 😂