So, I haven't experienced this in my own life; but, it's a pretty common thing on the internet to see a trans woman getting offended by somebody referring to her as "sir."
Okay, given my specialty at work, it's pretty rare for me to be running the show. There is a biological woman at work, with whom I work regularly, who I honestly find attractive, who is often the run of show.
The last time I worked with her, she asked me to do something. I said, "Yes sir." I meant it completely out of respect. Still, I corrected myself and said, "Yes ma'am." She just chuckled and said, "Either way."
That's how adults operate in the world.