Curcumin & Cancer

in medical •  3 years ago 

"Curcumin has long been used in Asian medicine to treat a variety of illnesses. Now some research suggests that curcumin may help prevent or treat cancer."
https://www.mayoclinic.org/diseases-conditions/cancer/expert-answers/curcumin/faq-20057858

"piperine is the major active component of black pepper and, when combined in a complex with curcumin, has been shown to increase bioavailability by 2000%."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/

"Research has shown lower rates of certain cancers in countries where people eat more curcumin. This is at curcumin levels of about 100mg to 200mg a day over long periods of time.

A few laboratory studies on cancer cells have shown that curcumin has anti cancer effects. It seems to be able to kill cancer cells and prevent more from growing. It has the best effects on breast cancer, bowel cancer, stomach cancer and skin cancer cells.

At the moment there is no clear evidence in humans to show that turmeric or curcumin can prevent or treat cancer."
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/complementary-alternative-therapies/individual-therapies/turmeric

"The anticancer mechanisms of curcumin have been extensively studied."
https://pubmed.ncbi.nlm.nih.gov/31223280/

"curcumin exhibits potent inhibitory effects on breast cancer"
https://www.sciencedirect.com/science/article/pii/S2213453018300533

"In a study conducted last year and published in the journal PLoS One, researchers from the University of Kansas‘ Cancer Center and Medical Center found that curcumin, the active ingredient in the spice turmeric, has the power to inhibit the growth of esophageal cancer cell lines.
In the study, the researchers observed multiple effects sparked by curcumin. First, curcumin treatment was found to halt proliferation in esophageal cancer cell lines. This means that cancer cells can no longer multiply as a result of cell growth or cell division. Further, curcumin was found to trigger apoptosis of cancer cells – programmed cell death."
https://naturalsociety.com/curcumin-inhibit-esophageal-cancer-cell-growth/

"curcumins inhibit cancer at initiation, promotion and progression stages of development."
https://pubmed.ncbi.nlm.nih.gov/1578097/

Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905673/

Curcumin inhibits cell proliferation and motility via suppression of TROP2 in bladder cancer cells
https://pubmed.ncbi.nlm.nih.gov/29901071/

Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling
https://pubmed.ncbi.nlm.nih.gov/25550533/

Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling
https://pubmed.ncbi.nlm.nih.gov/29901164/

Curcumin and quercetin synergistically inhibit cancer cell proliferation in multiple cancer cells and modulate Wnt/β-catenin signaling and apoptotic pathways in A375 cells
https://www.sciencedirect.com/science/article/abs/pii/S0944711318305075

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