Medium-Chain Fatty Acids & Enveloped Viruses

in medical •  5 years ago 

"Coronaviruses (like SARS-CoV-2) are enveloped viruses which possess a unique replication strategy with distinctive biological characteristics."
https://phenomenex.blog/2020/03/24/sars-cov-2/

"Fatty acids called Medium Chain Fatty Acids or Medium Chain Triglycerides are lipids that have been shown to inhibit certain viruses."
https://www.naturalmedicalcare.com/2009/04/27/improving-immune-system-with-monolaurin/

"Short-chain and long-chain saturated fatty acids had no or a very small antiviral effect at the highest concentrations tested. Medium-chain saturated and long-chain unsaturated fatty acids, on the other hand, were all highly active against the enveloped viruses, although the fatty acid concentration required for maximum viral inactivation varied by as much as 20-fold."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC174645/

"The medium chain fatty acids of coconut oil, and primarily lauric acid, have been known to destroy enveloped viruses by researchers for many years."

"Three mechanisms have been proposed to explain the antiviral activity of lauric acid and monolaurin: first, they cause disintegration of the virus envelope; second, they can inhibit late maturation stage in the virus replicative cycle; and third, they can prevent the binding of viral proteins to the host cell membrane."
https://coconutoil.com/coconut-oils-history-in-destroying-viruses-including-coronaviruses/

"Thus, emulsions of fatty acids and monoglycerides, especially 1-monoglyceride of capric acid, monocaprin (MC), inactivate enveloped viruses such as herpes simplex virus, respiratory syncytial virus, parainfluenza virus type 2 and influenza virus type A in suspension"

"Medium-chain saturated fatty acids and monoglycerides and long-chain unsaturated fatty acids have generally the highest microbicidal activity and rapidly kill enveloped viruses such as herpes simplex virus (HSV), HIV type 1 (HIV-1), the lentivirus maedivisna virus, respiratory syncytial virus and parainfluenza and influenza viruses"
https://www.researchgate.net/publication/8056120_Virucidal_activities_of_medium-_and_long-chain_fatty_alcohols_fatty_acids_and_monoglycerides_against_herpes_simplex_virus_types_1_and_2_Comparison_at_different_pH_levels

"MCTs contain fatty acids that have a chain length of 6–12 carbon atoms. They include caproic acid (C6), caprylic acid (C8), capric acid (C10), and lauric acid (C12).

Scientists have known for years that lauric acid (C12) surrounds and destroys viruses."
https://thehealthedge.com/2020/02/18/can-coconut-oil-kill-the-coronavirus/

"Coconut oil has been found to fight viral infections due to the presence of medium chain fatty acids in it that break down the lipids present in the envelope of viruses thereby killing the pathogenic viruses."
https://healthyy.net/superfoods/coconut-oil-for-infectious-diseases

"The action attributed to monolaurin is that of solubilizing the lipids and phospholipids in the envelope of the virus causing the disintegration of the virus envelope."
https://www.peacefmonline.com/pages/comment/features/202004/404406.php

"According to a study published in the Journal Evidence Based Complementary and Alternative Medicine, when unrefined coconut oil is consumed, “the MCTs are broken down into individual medium chain fatty acids and monoglycerides, which can kill or inactivate pathogenic microorganisms inside the body. The antiviral action, attributed to monolaurin (the monoglyceride of lauric acid), is that of solubilizing the lipids and phospholipids in the envelope of the pathogenic organisms causing the disintegration of their outer membrane."
https://mariamarlowe.com/blog/the-top-9-anti-viral-foods/

"Medium chain fatty acids (MCFA), which consist of 6 to 12 carbon atoms, have emerged as a promising technology to disrupt virus activity within feed, potentially due to interaction with the viral membrane, preventing viral replication"
https://academic.oup.com/jas/article/98/6/skaa159/5843591

"Monolaurin is known to inactivate lipid-coated viruses by binding to the lipid-protein envelope of the virus, thereby preventing it from attaching and entering host cells, making infection and replication impossible.[12] Other studies show that Monolaurin disintegrates the protective viral envelope, killing the virus."
https://en.wikipedia.org/wiki/Monolaurin

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