مطالعات نشان داده است که مصرف داروهای پایین آورنده‌ی اسید معده با سطح پایین‌تر ویتامین B12 در ارتباط است.
داروهای پایین آورنده‌ی اسید معده شامل مهار کننده‌های گیرنده‌ی H2 هیستامین مانند رانیتیدین و فاموتیدین و مسدود کننده‌های پمپ پروتونی مانند اومپرازول و پنتوپرازول هستند. مصرف بالا و مداوم این داروها با کمبود ویتامین B12 ارتباط دارد.
البته معنای این مطلب این نیست که مصرف این داروها قطعاً موجب کمبود ویتامین B12 و بروز کم‌خونی مگالوبلاستیک می‌شود. ولی لازم است که این داروها فقط به میزان لازم و به مدت درست مصرف شوند. در صورتی که درمان کوتاه‌مدت با این داروها مؤثر باشد، نباید به‌صورت مداوم مورد استفاده قرار گیرند.
یک مقاله‌ی مروری جدید، توصیه‌های مفید برای مصرف طولانی‌مدت داروهای مهار کننده‌ی پمپ پروتون را ذکر کرده است. در این مطالعه، انجام تست ویتامین B12 و یا مصرف بیش از حد نیاز ویتامین B12 در حین درمان طولانی‌مدت با مهار کننده‌های پمپ پروتون به‌صورت روتین توصیه نشده است.
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This post has received a 24.76% upvote from @msp-bidbot thanks to: @danai. Delegate SP to this public bot and get paid daily: 50SP, 100SP, 250SP, 500SP, 1000SP, 5000SP Don't delegate so much that you have less than 50SP left on your account.
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You got a 41.52% upvote from @flymehigh courtesy of @danai!
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You got a 30.86% upvote from @luckyvotes courtesy of @danai!
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You got a 22.28% upvote from @brandonfrye courtesy of @danai!
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You got a 23.56% upvote from @upyou thanks to @danai! Send at least 0.1SBD or 0.1STEEM to get upvote for next round.
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This post has received a 11.29 % upvote from @boomerang.
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To increase power #uptove
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I was summoned by @danai. I have done their bidding and now I will vanish...
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