It's interesting and bizarre, and the visual creativity is obviously there.
But...
It's a very creepy story that has a lot of uncomfortable elements involving sex that borders on non-consensual / pedophile kind of tropes because in spite of having an adult woman's body, Emma Stone's character is emotionally and intellectually a child or at most a teenager for nearly the whole film.
And it's not like the issue of consent and the child-like aspects of the protagonist is really well-explored or even addressed by the men she has sex with, so the film is obviously not trying to be about those kinds of issues (though in some ways, it really should be)... And...It's kind of like Candide, in that it's a bit of a philosophical odyssey, where Emma Stone figures out what she believes and who she is by exploring the world -- first leaving her comfortable home and her father / creator; then discovering bad people; then leaving the bad people behind; and eventually becoming the surgeon her father sort of wanted her to be.
But unlike Candide, there's not much to think about in any of the situations she finds herself in... or at least, the movie doesn't care if you think about them.
In any case, it's an interesting movie as a movie... and Emma Stone absolutely deserved her Oscar for it. But that's about it.