The results of research from a team of John Hopkins University scientists managed to uncover the mystery of why the skin feels itchy. Scientists have discovered nerve cells that are associated with the itching sensation. The findings are considered as a major breakthrough for relieving itching.

Many early experts suspected pain and itching receptors were related. But a team from Johns Hopkins University found that dMrgprA3 + nerve cells specifically detect itching sensations and do not detect pain.

Scientists have been looking for special itchy cells for decades. The presence of these neurons was undoubtedly following the observation that they also respond to painful stimuli.

To identify itchy cells, Xinzhong Dong, a neuroscientist at Johns Hopkins University in Maryland, United States, genetically engineered mice that had nerve cells that glowed green when itching struck.

The researchers then put several compounds in the mouse, such as histamine and active ingredients in itchy powder to look for nerves that glow green. The researchers then turned off the flaming nerves, and found mice with scuffed skin due to much less scratching.

Xinzhong Dong and his team hope they can silence these cells to develop better antigatal treatment. Their study opens a new way to study itching and develop anti-pruritus therapy.