Some individuals have a tyrannical selfplex that is severely repressive because it is very fragile and constantly in a state of threatened overthrow. The subversive selfplex in such a brain may be an even more repressive and depressive one, a repository of all unacceptable and derogatory memes. When such a fragile selfplex is overturned through new meme infusion (e.g., failure memes) under stress, the new selfplex may manifest severe depression.
Such a memetic revolution may also result in a paralysis of the executive function, i.e., the ability to manipulate memes, resulting in psychotic disorganization.
Paralysis of the executive function puts the brain in a state of perpetual mind-wandering, wakeful dreaming. During dreaming, the brain re-organizes its memories, the content of dreams reflects aspects of memory consolidation taking place. When a mind is broken, the amount of work required to re-build it is large, and the body enters a a perpetual dream state as an inflammatory response.
Variations in cortisol (and other neurotransmitters) determine the functional status of hippocampal ↔ neocortical circuits, thereby influencing the memory consolidation processes that transpire during sleep. During the schizo-psychotic collapse, increased cortisol levels contribute to the re-building of the mind.
Much like anti-inflammatory pharmaceuticals can exacerbate disease, anti-psychotics prevent the re-building process. In other words, psychosis is necessary for the brain to re-build, and visual and auditory hallucinations are part of the memory consolidation process.
People fear what they do not understand, and they instinctively want to rid the body of fever, and by doing so they kill people.
Meaning people will come out of a psychotic state on their own?
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The schizo-psychotic collapse is a reconstruction process, and a rejection response where the brain rejects the memes which it has integrated into itself. From early childhood, memes enter the brain that stand for social norms, codes of conduct, and ways of relating with people. These cultural memes naturally co-opt genetic imperatives for food, sex, and dominance and form strong mutually supporting memeplexes. (Leigh, 2010)
The rejection of these memeplex which are integrated with the limbic system and gene-based imperatives requires memory consolidation that goes far beyond an average nights sleep. The brain is rejecting its own conditioning.
The paralysis of the executive function allows memory consolidation, and if this "inflammatory response" is reduced pharmacologically, then that prevents the memory consolidation and the reconstruction process.
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