US and Chinese officials have exchanged sharp rebukes in the first high-level talks between the Biden administration and China, taking place in Alaska.
Chinese officials accused the US of inciting countries "to attack China", while the US said China had "arrived intent on grandstanding".
Relations between the two superpowers are at their most strained for years.
The US has pledged to raise contentious issues such as Beijing's treatment of Uighur Muslims in Xinjiang.
The ill-tempered talks in Anchorage involved Secretary of State Antony Blinken and national security adviser Jake Sullivan on the US side, facing off with China's most senior foreign policy official, Yang Jiechi, and foreign minister Wang Yi.
Are the US and China in a new 'Cold War'?
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In a blunt opening statement, Mr Blinken said the US would "discuss our deep concerns with actions by China, including in Xinjiang, Hong Kong, Taiwan, cyber attacks on the United States, economic coercion of our allies".https://www.getrevue.co/profile/op-wano-arc-ep-966/
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"Each of these actions threaten the rules-based order that maintains global stability," he said.
In response, Mr Yang accused Washington of using its military might and financial supremacy to suppress other countries.
"It abuses so-called notions of national security to obstruct normal trade exchanges, and incite some countries to attack China," he added.
Mr Yang said human rights in the US were at a low point, with black Americans being "slaughtered".
Mr Sullivan hit back, saying Washington did not seek a conflict with China, but added: "We will always stand up for our principles for our people, and for our friends."
Can the US and China work together?
The exchange, which took place in front of the world's media, went on for more than an hour.
Afterwards, the US delegation accused China of violating the agreed protocol of two minutes of opening remarks by each side.
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"The Chinese delegation... seems to have arrived intent on grandstanding, focused on public theatrics and dramatics over substance," a senior administration official said.
The official said the US would continue with the talks as planned, adding that "exaggerated diplomatic presentations often are aimed at a domestic audience".
The BBC's Barbara Plett Usher says the talks are the first chance for the Biden administration to show how it intends to deal with what Mr Blinken has called "the biggest geopolitical test of the 21st century".
China is looking for a reset after relations hit rock bottom under the Trump administration, our correspondent adds. Mr Wang has said that Beijing is ready to reopen "constructive dialogue."
The meeting between senior Biden administration officials and their Chinese counterparts marks the first face-to-face opportunity to gauge the dynamics of the relationship between the two most important global powers.
Secretary of State Antony Blinken and National Security Adviser Jake Sullivan will meet with China's top diplomat Yang Jiechi and Foreign Minister Wang Yi in Alaska on Thursday.
There are no illusions in the Biden team. Ahead of the meeting Mr Blinken noted this was "not a strategic dialogue" and there was "no intent at this point for a series of follow-on engagements".
"These engagements," he noted, "if they are to follow, really have to be based on the proposition that we're seeing tangible progress and tangible outcomes on the issues of concern to us with China."
Relations between the US and China are the worst they have been for many years and look set to become worse still. Well before his appointment Mr Sullivan, co-authored an article in Foreign Affairs magazine with Mr Biden's top Asia adviser - Kurt Campbell - which bluntly stated that "the era of engagement with China has come to an unceremonious close".
It has become commonplace to describe the US-China relationship as a new "Cold War", a reference to the generation-long rivalry between the US and the Soviet Union that cast a shadow over the latter half of the 20th Century.
How you characterise the relationship between Washington and Beijing matters. It helps to determine the sorts of questions that we ask and the answers that we receive. It sets the parameters for policy options, drawing us down some paths and perhaps blocking off other avenues. Using historical analogies is often said to be helpful in clarifying options, context and dilemmas. But others argue that it can be counter-productive. History does not repeat itself in this way and differences may outweigh similarities.
If by "Cold War" one means a great titanic struggle involving all aspects of national power waged between two incompatible political systems, then clearly the US-China rivalry has echoes of the US-Soviet confrontation.
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