"Several studies have suggested that silver nanoparticles (AgNPs) have the potential to treat human cancers, including leukemia. However, the detailed cellular mechanisms for AgNPs to inhibit the growth of leukemic cells and their efficacy on clinical isolates of leukemic patients are not elucidated."
https://pubmed.ncbi.nlm.nih.gov/24734519/
"Silver nanoparticles (AgNPs) have anti-cancer effect. However, whether and how these particles could inhibit the growth of acute myeloid leukemia (AML) cells is unclear."
https://pubmed.ncbi.nlm.nih.gov/23876760/
"The researchers went on to state that they wanted to study the cellular mechanisms through which “silver nanoparticles inhibit the growth of leukemic cells.” They found that silver nanoparticles enter leukemic cells and locate in endosomes, which are membrane-bound vesicles found in the cytoplasm of virtually every human and animal cell. Once inside the leukemic cell, the silver nanoparticles triggered the generation of reactive oxygen species, causing “cytotoxicity and apoptosis.” In other words, the leukemic cancer cells self-destructed."
https://thesilveredge.com/study-the-cellular-uptake-and-cytotoxic-effect-of-silver-nanoparticles-on-chronic-myeloid-leukemia-cells/