- Despite its pre-evolution Nidoran♀ and Nidorina's male counterpart Nidorino being able to breed, Nidorina and its evolution Nidoqueen are unable to breed.
- This also makes Nidorina and Nidoqueen the only two Pokémon that cannot breed even though their pre-evolution can breed.
- Nidorina's Shiny coloration is similar to Nidorino's regular coloration and vice versa.
- Nidorina and its pre-evolution share their category with their male counterparts Nidoran♂ and Nidorino. They are all known as the Poison Pin Pokémon.
