Great read.
Opioid pain relievers, e.g oxyconton, morphine, heroin. All hit the opioid receptors in our brains.
These are very concentrated forms of opiate which our body was never originally designed t consume, while raw opium is a much more natural, safer form of opiate.
Pharmaceuticals have ruined opiates for us you might say by giving us highly concentrated opium while raw opium is a lot more natural.
All plants are to be respected, clearly no respect for this plant by most pharmaceutical companies resulting in what we see above by @scottybuckes. Same goes for cocaine, the more concentrated and further away from the natural form the more problems we get.