None. The downside to plastic is it's more prone to scratching, which makes it more prone to hosting infection. The downside to glass is how fragile it is, and lots of people wind up with injuries because of breakage.
I use plastic, even in my professional batches.
I have a couple 6 gallon glass bottles and doubt I'll ever buy more. They are a real bear to shake and carry. It is dangerous as you said too. The 3 gallon ones are easy to handle however.
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You can get/make frames for the glass ones to help out a bit with the dangers. My next step will be stainless steel though.
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Yes, I'm actually thinking of a simple counter setup. I'll leave the brew bottles on a raised counter to age. Then I'll rack/bottle them right from the counter top. There are so many ways to improve the process though, but I'm limited to not having a dedicated production location within my home or an out building... yet.
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