Peptide Vaccine
"Most existing vaccines are prepared from an attenuated version of the pathogen or from inactivated disease-causing organisms or a suitable part of it e.g. a toxin. However, often the antigen to which the immune system responds is a relatively small number of amino acids or peptide.
A possible alternative approach to immunization would therefore be to identify the peptide sequences that trigger a protective immune response and to use completely synthetic versions of these as the vaccine substance. Because they would be synthetic, there would be no risk of mutation or reversion, little or no risk of contamination by pathogenic or toxic substances, and chemical manipulation of the peptide structure could possibly increase stability and decrease unwanted side effects seen in the native sequence."
https://www.who.int/biologicals/vaccines/synthetic_peptide_vaccines/en/
N. Protien
"Viral components like spike and nucleocapsid proteins trigger an immune response in the host to eliminate the virus."
https://pubmed.ncbi.nlm.nih.gov/32849654/
M. Protien
"The M protein of SARS-CoV holds dominant cellular immunogenicity. This, together with previous reports of a strong humoral response against the M protein, may help to further explain the immunogenicity of SARS and serves as potential targets for SARS-CoV vaccine design."
https://pubmed.ncbi.nlm.nih.gov/20831383/
S. Protien
"All three antigens (S1+S2 ectodomain, S1 domain, and RBD), but not S2, generated strong neutralizing antibodies against SARS-CoV-2."
https://stm.sciencemag.org/content/12/550/eabc3539
E. Protien
"Besides its multifunctional properties, E protein is also highly immunogenic attracting the attention of diverse research groups that target this protein for the development of antigen-based studies including those aimed at developing immunodiagnostic tools and prophylactic oriented studies [11,16]."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241347/
Fusion Peptide
"FP is a short segment of 15–20 conserved amino acids of the viral family, composed mainly of hydrophobic residues, such as glycine (G) or alanine (A), which anchor to the target membrane when the S protein adopts the prehairpin conformation."
https://www.nature.com/articles/s41401-020-0485-4
Zinc Ionophore + Zinc + Antibiotics
"This prior discovery appears to validate the recent report6 of Vladimir Zelenko MD, a New York-based physician who has treated 699 consecutive cases of COVID-19 … with complete 100% success. His treatment protocol includes oral zinc, chloroquine as a zinc ionophore and an antibiotic (azithromycin).”"
https://www.lewrockwell.com/2020/04/joseph-mercola/how-to-improve-zinc-uptake-to-boost-immune-health/
Zinc
"Zinc promotes immune functions and helps people resist infectious diseases"
https://www.cdc.gov/nutrition/micronutrient-malnutrition/micronutrients/index.html
"Each unit increase of plasma zinc at admission to hospital was associated with a 7% reduced risk of in-hospital mortality. Having a plasma zinc level lower than 50 mcg/dl at admission was associated with a 2.3 times increased risk of in-hospital death compared with those patients with a plasma zinc level of 50 mcg/dl or higher."
https://www.lewrockwell.com/2020/10/joseph-mercola/zinc-is-key-for-covid-19-treatment-and-prevention/
*"A study from India involving 47 Covid patients and 45 healthy individuals showed significantly lower zinc levels in Covid patients when compared to the healthy individuals.
Among the Covid patients, 27 (57.4 per cent) were found to be zinc-deficient. These patients were found to have higher rates of complications, acute respiratory distress syndrome, corticosteroid therapy, prolonged hospital stays, and increased mortality. The hospital stay was 7.9 days among the zinc-deficient patients, and 5.7 days among individuals with enough zinc level."*
https://theprint.in/health/the-importance-of-zinc-in-fight-against-covid-and-what-studies-on-the-nutrient-say/539562/
"Zinc with an ionophore was associated with increased rates of discharge home and a 24% reduced risk of in-hospital mortality among COVID-19 patients, while neither zinc alone nor the ionophore alone reduced mortality."
https://europepmc.org/article/MED/33140042
*"The use of zinc was not associated with any difference in length of hospital stay, duration of ventilation, or any specific settings used in ventilation.
However, zinc was associated with a 49% lower risk of either being transferred to hospice or dying, a 44% decreased chance of requiring invasive ventilation, and a 56% increased likelihood of being discharged from the hospital and released to home care."*
https://chrismasterjohnphd.com/covid-19/the-first-zinc-and-covid-19-study-in-humans-very-promising
*"Between March 15, 2020, and April 30, 2020, doctors measured fasting levels of zinc in 249 Covid patients admitted to a university hospital in Barcelona, Spain. Zinc levels averaged 61 micrograms per deciliter of blood (mcg/dL), and among those who later died in the hospital, average zinc levels were 43 mcg/dL.
Overall, those whose zinc levels fell below 50 mcg/dL were 2.3 times more likely to die in the hospital than those with levels at or higher than 50. While the infection was active, those with better zinc levels also had lower levels of interleukin-6, the proteins that signal systemic inflammation."*
https://betsys-health-foods.myshopify.com/blogs/news/zinc-and-vitamin-d-linked-to-better-covid-outcomes
Zinc Ionosphore
"Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses"
https://pubmed.ncbi.nlm.nih.gov/21079686/
"Quercetin plus zinc is being tested as an anti-viral in human clinical trials for the treatment of Covid-19. The combination had already made it through animal trials for use against Ebola and SARS-CoV1, and was approved by the FDA for human clinical trials. Plans are underway for a large scale trial in China for patients with Covid-19."
https://dadamo.com/dangerous/2020/04/07/covid-19-chloroquine-zinc-and-quercetin/
*"Therefore, drugs that described as zinc ionophores could be used with zinc supplement to act as antiviral against many RNA viruses including SARS-CoV-2 Quercetin is natural compound act as zinc ionophore to cause zinc influx intracellular.
Quercetin is a safe natural anti-oxidant and anti-inflammatory polyphenolic compound that found in various natural sources include onion, red grapes, honey and citrus fruits. It was shown that quercetin has the ability to chelate zinc ions and act as zinc ionophore."*
https://clinicaltrials.gov/ct2/show/NCT04468139
"Quercetin kills viruses in laboratory dishes, though the mechanisms are not entirely clear."
https://www.lifeextension.com/magazine/2012/9/quercetin-broad-spectrum-protection
*"EGCG, a component of Green Tea Extract (GTE), is one such zinc ionophore.
The EGCG can latch on to the zinc ion and carry it into the cell cytoplasm, where the zinc inhibits a viral protein called replicase. Replicase (or RdRp) makes copies of viral RNA. Both SARS-CoV-1 and SARS-CoV-2 have a replicase protein. The replicase protein complex (made up of several proteins) is blocked by zinc ions, preventing the virus from making copies of its RNA. This stops the virus from multiplying."*
https://covid.us.org/2020/09/30/covid-19-and-green-tea-extract-egcg/
"Further research on SARS-CoV-1 and SARS-CoV-2 and GTE found that EGCG (epigallocatechin gallate) and other Catechins are able to inhibit the virus directly, even without zinc."
https://covid.us.org/2020/09/30/covid-19-and-green-tea-extract-egcg/
Copper (Antibiotic / Antiviral)
"If instead of stealing useful metals like zinc, Johnson could deliver toxic copper to the virus’s spike proteins, it could be rendered inoperable."
https://research.arizona.edu/stories/could-copper-disable-virus-behind-covid-19
"When a microbe lands on copper, ions blast the pathogen like an onslaught of missiles, preventing cell respiration and punching holes in the cell membrane or viral coating and creating free radicals that accelerate the kill, especially on dry surfaces. Most importantly, the ions seek and destroy the DNA and RNA inside a bacteria or virus, preventing the mutations that create drug-resistant superbugs. “The properties never wear off, even if it tarnishes,” Schmidt says."
https://www.smithsonianmag.com/science-nature/copper-virus-kill-180974655/
Silver (Antibiotic / Antiviral)
"Bacteria killed by silver store it in their cells, making them deadly to other bacteria. Silver nanoparticles are visible inside the bacteria as white spots."
https://www.sciencemag.org/news/2015/05/silver-turns-bacteria-deadly-zombies
"Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds"
https://pubmed.ncbi.nlm.nih.gov/21812950/
*"The Reference Dose (RfD) that it describes is the guideline that all other EPA agencies, including those that set the drinking water standards, refer to as the most authoritative guideline.
In reading the document, note that the RfD that is represented as 5E-3 mg/kg/day should be read as follows:
5 to the exponent of minus 3 (0.001) = 0.005 milligrams per kilogram of body weight per day"*
http://www.silverfacts.com/safety.html
Mortal Oscillatory Rate
"Dr. Royal Rife discovered what’s known as the “Mortal Oscillatory Rate” for numerous pathogenic organisms, a principle by which vibration through harmonic frequency can break down harmful bacteria, viruses, and other microorganisms that can cause disease."
https://theguyerinstitute.com/acoustic-lightwave-therapy/
*"Scientists may one day be able to destroy viruses in the same way that opera singers presumably shatter wine glasses. New research mathematically determined the frequencies at which simple viruses could be shaken to death.
"The capsid of a virus is something like the shell of a turtle," said physicist Otto Sankey of Arizona State University. "If the shell can be compromised [by mechanical vibrations], the virus can be inactivated.""*
https://www.livescience.com/7472-kill-viruses-shake-death.html
"Over the course of 15 months, Dr. Holland and his team eventually came across a particular combination of two related frequencies that would completely shatter the cells. The frequencies consisted of one high and one low. The high frequency had to be eleven times higher than the low, which in music is known as the 11th harmonic. At this frequency, micro-organisms start shattering like crystal glass."
https://livelovefruit.com/researchers-prove-sound-frequencies-can-kill-cancer/
Methods for determining therapeutic resonant frequencies
United States Patent 7280874
https://www.freepatentsonline.com/7280874.html
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