Science Blind Draw : Antibody (Answer checking)

in science •  7 years ago 

Last time, me and @nanosesame decided to try on a little project, Science Blind Draw. Our first test topic was Human Anatomy, it went pretty well and we decide to try another round and here is @nanosesame's 2nd post, please go check other post of @nanosesame for her other talented works~

Screen Shot 2018-05-21 at 10.13.34 pm.jpg

Before I start explaining, I must state that I really really love this piece of art, if i ever get rich in crypto, I will definitely hire @nanosesame to draw this one with real paint for me XD (thought she will be richer than I am, very likely)

Her art is quite precise this time, given the only clue was Y shaped protein that binds microbe, on the right of the her art actually shows the real case scenario of how an antibody binds to a microbes (this case was a virus). If you guys have been following me, I often state the importance of vaccinations and antibodies plays a critical role in vaccinations and hence, my choice of topic for this time.

Antibodies are immune proteins produce by the host (yourself) in response to the encountering of antigen. Antigen are things that normally doesn't belongs to you, frequently foreign things that belongs to bacteria, virus, fungi, these things should be remove from our body, so those type of antigens will trigger our immune response. The site for binding of the antigen from th Y shape antibody is actually from the upper V shape ends. As from the image, the grey region, the antigen binding site. While the lower I part of the Y is responsible to trigger other pathogen clearing process or enhances the activities of the antibodies.

And if we want to look further deep into the antibodies, each antibody comprise of 2 halves, with each halves containing a light chain and a heavy chain. Each chain comprise of a variable region and a constant region. The variable region is what allows our immune system to generate different combinations to recognise different antigen. Yet, this comes in a draw back, that is if antibodies some how has its variable region recognising non-harmful things which we encounter in daily life or even recognise our own tissues, this will cause allergy or autoimmune disease.

This is what happen when we are allergic to peanut, to eggs, to sea food, our immune system recognise those protein/ molecules in the food as potential threat, and triggered immune response. This can be mild like regional rash to life threatening suffocation.

So for @nanosesame's drawing, her Y shape antibodies are some what correct or as abstracted, while the microbes should be much larger, as virus is still 100-1000X larger than the antibodies, not to mention, another significant size difference between size of virus and that of bacteria~

For more information related to antibodies, please visit my source:
http://www.scienceclarified.com/Al-As/Antibody-and-Antigen.html
https://www.bio-rad-antibodies.com/immunoglobulin-antibody.html
for more information~


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First I want to wish you congratulations for your blog is an excellent job I hope you follow me @ luisa-pinto and can count on your support in my blog

thanks~

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So allergy to egg, milk caused by over react is a "bug" of this Y shape thing :-/ ?
Btw, I think my guess will get more and more precise as I also learn more through the answer post....may be after 100 rounds xDDD

the Y thing is just a result, the bug is at early process~
That's good, at least i am educating 1 person via my steemit post~