@suesa why not flox the gene of interest you want to knockout, and do tissue specific Cre expression by throwing in an inducible Cre driven by a neuron specific promoter? I guess it depends on what model system you're using
RE: Let's Splice! (My Research, Vol. 3)
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Let's Splice! (My Research, Vol. 3)
That's a good question, I'd have to ask my supervisor. He's been working on this for a while tho and what you suggested is the traditional way, there's probably a reason why we're not doing it like that. It's mice btw.
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