He's currently filming the Britain's Got Talent auditions with co-host Declan Donnelly, in the midst of his from estranged wife Lisa Armstrong.
And Ant McPartlin, 42, reportedly 'broke down in tears' after watching a moving audition at last week's trials in London.
After a magician shared a heartbreaking story about cancer, a show source told The Mirror: 'This story seemed to really strike a chord with Ant.'
The presenter was allegedly comforted by his co-host and friend Dec as the magic practitioner revealed his wife and daughter suffered from cancer.
However, a spokesperson for Ant told MailOnline: 'Ant did not burst into tears at this act and Dec did not have to comfort him.'