This is so true, there is nothing in this material world that can give lasting hope and contentment to spiritual beings. Those of us who have not had our conscience seared by dulling our senses in order try to fit in in this world system acutely feel the missing puzzle pieces to our soul.

There are many counterfeit paths to peace that compete for our attention. Some have shunned material pursuits, turning to relationships and have had some more success, but these too fail to satisfy. Maybe the partial peace we can have from cultivating relationship with other spiritual beings hints at the truth.
Each of us, in the realm of what we believe, are on a path of our own choosing. No matter our circumstances or history, we all control absolutely what we believe.
If we were created for a purpose, then I don't believe we will be truly content until we begin to fulfill that purpose. I have come to the conclusion that we were created by a creator who's purpose for us is to be in relationship with him. We the created have severed our bond to the creator and caused general destruction and mayhem in the earth that he gave us, but there is hope...
He has provided us a path to re-forge the bond that was broken, and that path was blazed by his own son, known to us as Jesus of Nazareth.
Others may have their own path, but I only speak of my own experience. Nothing in this life or experience brought me to peace and rest until I accepted that the cross and miraculous resurrection of Christ were meant as a lifeline to me personally, and to everyone who chooses to take it.
Now that the missing puzzle piece of my soul is in place, every good thing in this life has inspired gratitude, and every struggle has inspired hope, patience, and peace. In every way I feel content and am at rest. Free of my own conflict, I now find it eminently easier to find the capacity to help others.
I encourage you on your path, and I pray that wisdom guides you and leads you to truth, peace and rest.