I've never played the Fallout series (it's not the genre I typically play), and I usually don't enjoy MA-rated shows. But I'm enjoying this one!
It's got a mix of action and funny that's engaging.
I'm sure I'm missing almost all the references since I didn't play the games, but as a long-time player of Bethesda's other flagship series The Elder Scrolls, I did find this line funny:
"Yeah, well the Wasteland's got its own golden rule: Thou shalt get sidetracked by bulls**t every goddamn time."