By a News Reporter-Staff News Editor at Heart Disease Weekly -- Investigators publish new report on Immune System Diseases and Conditions - HIV/AIDS. According to news reporting originating from Durham, North Carolina, by NewsRx correspondents, research stated, “Cardiovascular disease (CVD) is an increasing cause of morbidity and mortality in human immunodeficiency virus (HIV)-infected adults; however, this population may be less likely to receive interventions during hospitalization for acute coronary syndrome (ACS). The degree to which this disparity can be attributed to poorly controlled HIV infection is unknown.”
Our news editors obtained a quote from the research from Duke University, “In this large cohort study, we used the National Inpatient Sample (NIS) to compare rates of cardiac procedures among patients with asymptomatic HIV-infection, symptomatic acquired immunodeficiency syndrome (AIDS), and uninfected adults hospitalized with ACS from 2009 to 2012. Multivariable analysis was used to compare procedure rates by HIV status, with appropriate weighting to account for NIS sampling design including stratification and hospital clustering. The dataset included 1,091,759 ACS hospitalizations, 0.35% of which (n=3783) were in HIV-infected patients. Patients with symptomatic AIDS, asymptomatic HIV, and uninfected patients differed by sex, race, and income status. Overall rates of cardiac catheterization and revascularization were 53.3% and 37.4%, respectively. In multivariable regression, we found that relative to uninfected patients, those with symptomatic AIDS were less likely to undergo catheterization (odds ratio [OR] 0.48, confidence interval [CI] 0.43-0.55), percutaneous coronary intervention (OR 0.69, CI 0.59-0.79), and coronary artery bypass grafting (0.75, CI 0.61-0.93). No difference was seen for those with asymptomatic HIV relative to uninfected patients (OR 0.93, CI 0.81-1.07; OR 1.06, CI 0.93-1.21; OR 0.88, CI 0.72-1.06, respectively).”
According to the news editors, the research concluded: “We found that lower rates of cardiovascular procedures in HIV-infected patients were primarily driven by less frequent procedures in those with AIDS.”
For more information on this research see: Lower likelihood of cardiac procedures after acute coronary syndrome in patients with human immunodeficiency virus/acquired immunodeficiency syndrome. Medicine , 2018;97(6):217-222. Medicine can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA. (Elsevier - www.elsevier.com; Medicine - http://www.journals.elsevier.com/medicine/)
The news editors report that additional information may be obtained by contacting M.E. Clement, Duke University, Duke Clin Res Inst, Durham, NC, United States. Additional authors for this research include L. Lin, A.M. Navar, N.L. Okeke, S. Naggie and P.S. Douglas.
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CITATION: (2018-04-29), New Findings Reported from Duke University Describe Advances in HIV/AIDS (Lower likelihood of cardiac procedures after acute coronary syndrome in patients with human immunodeficiency virus/acquired immunodeficiency syndrome), Heart Disease Weekly, 50, ISSN: 1532-4613, BUTTER® ID: 015528654
From the newsletter Heart Disease Weekly.
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