Antibiotic found in Nose that can Kill Superbug

in antibiotics •  8 years ago 

It is not often that something actually useful comes from the nose.

Yet German scientists credit bacteria in the modest human schnoz with creating an antibiotic that seems strong enough to kill skin diseases that are serious.

A kind of staph bacteria discovered in about 10% of people's noses, based on a study published in Nature produces the antibiotic.

Like a microscopic Game of Thrones, bacteria continuously conflict for dominance against germs that are competing. As valuable microbes kill off many of the poor ones that may make us ill people frequently reap the benefits of this germ warfare.

Some bacteria make their own chemical weapons, in the kind of antibiotics, to thwart their opponents. For 70 years, people have used these materials to treat diseases. While most antibiotics come from bacteria that live in earth, antibiotics have been discovered by scientists recently in the body, including one created by beneficial bacteria in the vagina.

The discovery of yet another antibiotic in the nose indicates that these earlier findings were not only flukes.

Overuse of antibiotics has led to antibiotic resistance, in which bacteria evolve in ways which make them hard as well as impossible to kill, in spite of the most effective drugs.

Many physicians now stress that we could be entering a "post-antibiotic age," in which individuals are prone to dying from common illnesses and routine operations carry tremendous dangers.

Yet you can find not many new antibiotics in the pipeline, Peschel said.

Antibiotics aren't difficult to develop. Many experimental ones prove too hazardous to use in people, said David Weiss, manager of the Emory Antibiotic Resistance Centre in Atlanta. The last new group of antibiotics was released more than 30 years past. Antibiotics happen to be similar to others already in use, making it easier for bacteria to become immune to them, he said.

Drug companies have little economic incentive to spend money on new antibiotics, which may require more than $1 billion dollars and a decade to develop. Antibiotics, which are normally taken for a week approximately, are much less lucrative than drugs taken for a long time, like cholesterol medicines.

In tests on mice, researchers found the new antibiotic, which they called lugdunin, could treat skin diseases resulting from kind of bacteria called MRSA, or methicillin-resistant Staphylococcus aureus, which can be immune to many different drugs. Along with your skin, MRSA may also infect the bloodstream and lining of one's heart.

Doctors have not yet examined the new antibiotic in people, Peschel said.

But the study suggestions at ways that analyzing the microbes of the body, together called the microbiome that was human, could bring about new treatments for disease, said an associate professor, Kjersti Aagaard
The antibiotic discovery is "a fantastic observation" that "talks to the power of initiation and sensible scientific insights," Aagaard said. "When we affect the body, along with the world around us, as a refined ecosystem, there will be never-ending wonders to be found at our fingertips, or the point of our nose." 

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