Association between vasectomy and risk of testicular cancer: A systematic review and meta-analysis

in asia •  7 years ago 

By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Research findings on Oncology - Testicular Cancer are discussed in a new report. According to news reporting originating in Guangdong, People’s Republic of China, by NewsRx journalists, research stated, “A number of researchers have reported that vasectomy is a risk factor for testicular cancer. However, this conclusion is inconsistent with a number of other published articles.”

Funders for this research include National Natural Science Foundation of China, Guangzhou Science Technology and Innovation Commission, The China Postdoctoral Science Foundation.

The news reporters obtained a quote from the research from the First Affiliated Hospital of Guangzhou Medical University, “Hence, we conducted this meta-analysis to assess whether vasectomy increases the risk of testicular cancer. We identified all related studies by searching the PubMed, Embase, and Cochrane Library database from January 01, 1980 to June 01, 2017. The Newcastle-Ottawa Scale (NOS) checklist was used to assess all included non-randomized studies. Summarized odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the difference in outcomes between case and control groups. Subgroup analyses were performed according to the study design and country. A total of eight studies (2176 testicular cancer patients) were included in this systematic review and meta-analysis. Six articles were case-control studies, and two were cohort studies. The pooled estimate of the OR was 1.10 (95% CI: 0.93-1.30) based on the eight studies in a fixed effects model. Two subgroup analyses were performed according to the study design and country. The results were consistent with the overall findings. Publication bias was detected by Begg’s test and Egger’s test and p values >0.05, respectively. Our meta-analysis suggested that there was no association between vasectomy and the development of testicular cancer.”

According to the news reporters, the research concluded: “More high-quality studies are warranted to further explore the association between vasectomy and risk of testicular cancer.”

For more information on this research see: Association between vasectomy and risk of testicular cancer: A systematic review and meta-analysis. Plos One , 2018;13(3):e0194606. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

Our news correspondents report that additional information may be obtained by contacting H. Duan, Dept. of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China. Additional authors for this research include T. Deng, Y. Chen, Z. Zhao, Y. Wen, Y. Chen, X. Li and G. Zeng.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1371/journal.pone.0194606. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2018, NewsRx LLC

CITATION: (2018-04-15), First Affiliated Hospital of Guangzhou Medical University Details Findings in Testicular Cancer (Association between vasectomy and risk of testicular cancer: A systematic review and meta-analysis), Medical Devices & Surgical Technology Week, 321, ISSN: 1537-1417, BUTTER® ID: 015446362

From the newsletter Medical Devices & Surgical Technology Week.
https://www.newsrx.com/Butter/#!Search:a=15446362


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