This build uses the following :
Biostar TB250-BTC Pro ($125)
Intel Celeron 3.9Ghz with Heatsink ($44)
Kingston Fury 16GB ($108)
250GB SSD ($65)
EVGA 1300W PSU ($220)
EVGA 1000W PSU ($140)
2PSU Adapter ($5)
Ver6 Powered USB Risers ($100 for 12)
Nvidia GTX 1060 6GB (6 pack EBay $1400)
AMD RX580 8GB OC (6 pack Amazon $2200)
Wire Rack Shelving Unit ($40)
Zip ties ($5)
Config file:
setx GPU_Force_64BIT_PTR 0
setx GPU_MAX_HEAP_SIZE 100
setx GPU_USE_SYNC_OBJECTS 1
setx GPU _MAX_ALLOC_PERCENT 100
setx GPU _SINGLE_ALLOC_PERCENT 100
EtherDcrMiner64.exe -epool eth-us-east1.nanopool.org:9999 -ewal (insert your Eth wallet address).(rig name)/(email) -epsw x mode 1 -ftime 10 -tstop 85 -tt 65 -fanmin 65 -fanmax 100 -cclock 1200 -mclock 2250 -cvddc 875 -mvddc 900 -dcri 8/12
This sets up the AMD cards decently -cvddc & -mvddc might need to be tweaked a bit.