I use a Ledger, note you can only install a handful of wallets on it at a time. This doesn't mean you lose anything between installs and uninstalls but it is very annoying to switch if you regularly use more wallets than it can support at once.
Also note that the manager app and the wallets are separate Chrome plugins and you can to close one and open the other manually.
The big advantage to the ledger is it supports a lot of coins and is adding coins pretty regularly.