Thats interesting on the toothpaste. I luckily have not noticed that side effect despite my bad teeth condition.
As for the negative effects, the only thing is that my body seems to get confused when I'm out of kombucha. It's like stopping a program midway and expecting something haha. I do feel generally better but i am sad I am out haha.
The detox effects I notice are that I just have to go to the bathroom suddenly, and a lot but i feel better as time goes on.