We compiled the evidence related to the use of the ketogenic diet in relation to its impact on the microbiome, epigenome, diabetes, weight loss, cardiovascular health, and cancer because there is a lack of a comprehensive, multi-faceted overview of the ketogenic diet (KD) in relation to health issues.
The KD diet has the potential to boost microbiome genetic diversity and the ratio of Bacteroidetes to Firmicutes.
Because the KD produces a signalling molecule called -hydroxybutyrate, it may have a favourable impact on the epigenome (BHB). KD has assisted diabetic people in lowering their HbA1c and lowering their insulin requirements.
As doctors and researchers look into the possible benefits, ketogenic diets are becoming more popular.
Nutritional ketosis, the ideal goal of ketogenic diets, is accomplished by decreasing carbohydrate intake, limiting protein intake, and boosting fat calories [1].
This carbohydrate limitation, in theory, enables the body to transition away from glucose metabolism as a primary source of energy. As a result, fat metabolism produces ketone bodies, a metabolic state in which the body prefers to use fat as its major fuel source.
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