Households in the wealthiest area of England and Wales have an average disposable income four times that of the poorest, according to Office for National Statistics estimates.
The average figure in Mickleover North, in Derby, in 2017-18 was almost £40,000 more than in St Matthews and Highfields North, Leicester, estimates suggest.
Derby also had the widest income gap between its richest and poorest areas.
London and south-east England had the highest proportion of wealthy areas.