Statements like Yellen's about crypto are like a dad telling his daughter not to date the rebel in the leather jacket (or whatever passes for badass nowadays.) Forbidden fruit and all that.
Smart regulation wouldn't be the worst thing in the world, but as much as Trump hates crypto, he definitely caused chaos regularly, which ironically shakes investors' faith in fiat and caused BTC to crest during the Capitol riot (a tragic day all around, but just sayin').
Stupid human emotion begets rising prices begets actual prudent investors begets further rising prices etc. BTC even cooled off yesterday and today, apparently because the world isn't going to hell anymore.
As BTC goes legit as regulation and large investors come in (for better or worse) it will be interesting to see if law enforcement leverages blockchains for investigations, since it's an immutable record (with legality and tech around it changing/advancing in new ways.)
Criminal elements may up their game and adopt privacy coins (XMR, ZEC, or something else) and the whole crypto market could diversify to other alts with use cases not even conceived of today. So BTC may finally lose it's 12-year first-mover advantage.
Bottom line: we'll be a'right in crypto. If government is unfriendly crypto goes elsewhere. That's sort of the point, although can be a double-edged sword.