Associations between dietary intakes of iron, copper and zinc with risk of type 2 diabetes mellitus: A large population-based prospective cohort study

in japan •  7 years ago 

By a News Reporter-Staff News Editor at Physician Law Weekly -- Current study results on Nutritional and Metabolic Diseases and Conditions - Type 2 Diabetes have been published. According to news originating from Osaka, Japan, by NewsRx correspondents, research stated, “Abnormal homeostasis of iron, copper and zinc has been included in the pathogenesis of type 2 diabetes mellitus (T2DM). However, the evidence of associations between dietary intakes of these elements and T2DM is limited.”

Financial support for this research came from Ministry of Higher Education.

Our news journalists obtained a quote from the research from Osaka University, “We thought to examine the association between dietary intakes of iron, copper and zinc with risk of T2DM in Japanese population. A prospective study encompassing 16,160 healthy Japanese men and women aged 40-65 years in whom the associations between dietary intakes of iron, copper and zinc, determined by a validated self-administered food frequency questionnaire, with risk of 5-year cumulative incidence of validated physician-diagnosed T2DM, were evaluated by logistic regression model. We ascertained 396 self-reported new cases of diabetes within 5-year period. Dietary intakes of iron (total and nonheme but not heme iron) and copper were positively associated with risk of T2DM; the multivariable OR in the highest versus lowest quartiles of intakes were 1.32 (1.04, 1.70; P-trend = 0.03) and 1.55 (1.13, 2.02; P-trend = 0.003), respectively. These associations were more evident in the high risk group; older, overweight, smokers and those with family history of diabetes. The dietary intake of zinc was inversely associated with risk of T2DM; the multivariable OR was 0.64 (0.54, 1.00; P-trend = 0.003), and such association was evident among younger subjects (age 40-55 years) only.”

According to the news editors, the research concluded: “Dietary intakes of iron and copper were associated with a higher risk, while dietary intake of zinc was associated with a reduced risk of T2DM in Japanese population.”

For more information on this research see: Associations between dietary intakes of iron, copper and zinc with risk of type 2 diabetes mellitus: A large population-based prospective cohort study. Clinical Nutrition , 2018;37(2):667-674. Clinical Nutrition can be contacted at: Churchill Livingstone, Journal Production Dept, Robert Stevenson House, 1-3 Baxters Place, Leith Walk, Edinburgh EH1 3AF, Midlothian, Scotland. (Elsevier - www.elsevier.com; Clinical Nutrition - http://www.journals.elsevier.com/clinical-nutrition/)

The news correspondents report that additional information may be obtained from H. Iso, Osaka University, Grad Sch Med, Dept. of Social Med, Public Hlth, Suita, Osaka 5650871, Japan. Additional authors for this research include E.S. Eshak, K. Maruyama, I. Muraki and A. Tamakoshi.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.clnu.2017.02.010. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2018, NewsRx LLC

CITATION: (2018-04-25), Data on Type 2 Diabetes Discussed by Researchers at Osaka University (Associations between dietary intakes of iron, copper and zinc with risk of type 2 diabetes mellitus: A large population-based prospective cohort study), Physician Law Weekly, 147, ISSN: 1551-5303, BUTTER® ID: 015527028

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