The fat cells of obese people contain large amounts of fat in the body. Because fat cells produce leptin in proportion to their size, obese people also have large amounts of leptin. Given the way leptin works, many obese people should naturally limit their food intake. In other words, their brains must know that a large amount of energy is stored. However, their leptin signals may not work. Although there is a lot of leptin, the brain does not see it.
This condition, known as leptin resistance, is now one of the main biological factors of obesity. If your brain does not receive the leptin signal, it will make the mistake of saying that your body is starving, even if enough energy is stored. This forces your brain to modify its behavior to restore the amount of body fat. Then your brain stimulates:
Your Brain Thinks That You Must Eat In Order To Prevent Starvation
Reduce energy consumption: In order to save energy, your brain decreases energy levels and burns fewer calories at rest. Eating more and exercising less is not the main reason for weight gain, but leptin resistance can be hormone deficiency. For many people struggling with leptin resistance, it is impossible to prepare to overcome the hunger signal caused by leptin.
Impact on Dieting
Leptin resistance can be one of the reasons why many diets do not help you lose weight in the long run. If you are resistant to leptin, losing weight will always reduce fat, which will cause a significant decrease in leptin levels, but your brain will not be able to change it at all. leptin resistance.
When leptin xi hormone type decreases, it leads to hunger, increased appetite, decreased motivation to exercise and a decrease in calories burned during rest. Then your brain thinks of your hunger and triggers various powerful mechanisms to replenish lost body fat. This can be a major reason for many people to lose weight soon after a yo-yo diet.
What Causes Leptin Resistance?
Several potential mechanisms have been identified behind leptin resistance. Inflammatory signals in your hypothalamus are an important cause of leptin resistance in animals and humans. An increase in free fatty acids in the blood can increase the metabolites of fat in your brain and interfere with leptin signaling.
Having high leptin: High leptin levels lead in the first place to leptin resistance. Many of these factors are exacerbated by obesity, which means that you can gain weight and become increasingly resistant to leptin over time.
Can Leptin Resistance Be Reversed?
The best way to tell if you are resistant to leptin is to look in the mirror. If you have a lot of body fat, especially in the abdominal cavity, you are almost resistant to leptin. It is not clear how leptin resistance can be changed, although there are many theories. Some researchers believe that reducing food inflammation can help restore leptin resistance. Focusing on an overall healthy lifestyle can also be an effective strategy.
essential knowledge about leptin
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