If you run a cryptocurrency mining rig- how to get the best performance

If you are running a rig with GPUs, you likely hear people in groups, etc. telling you what is best to mine for best profits. If you do not know yet, you can use whattomine.com, tell them what GPUs you are running, and they will tell you which coin is most profitable for your rig at that time, over the past 3 days, and over the past 24 hours