The Lancet Infectious Diseases: Rise of ampicillin resistance began years before human use -- likely triggered by overuse of penicillins in agriculture in the 1950s

in news •  7 years ago 

By a News Reporter-Staff News Editor at Agriculture Week -- -- Low doses of penicillin routinely fed to livestock in the 1950s in North America and Europe may have encouraged antibiotic-resistant bacteria to evolve and spread

Bacteria that can pass on genes resistant to ampicillin, one of the most commonly used antibiotics today, emerged several years before the widespread use of this antibiotic in humans, according to new research published in The Lancet Infectious Diseases.

Molecular analysis of historical samples of Salmonella by researchers at the Institut Pasteur (Paris, France) suggests that the ampicillin resistance gene (blaTEM-1) emerged in humans in the 1950s, several years before the antibiotic was released onto the pharmaceutical market. The findings also indicate that a possible cause was the common practice of adding low doses of penicillin to animal feed in the 1950s and 60s.

The study comes just weeks after WHO called for the end to routine antibiotic use to promote …

CITATION: (2017-12-14), The Lancet Infectious Diseases: Rise of ampicillin resistance began years before human use -- likely triggered by overuse of penicillins in agriculture in the 1950s, Agriculture Week, 191, ISSN: 1938-1794, BUTTER® ID: 014838920

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