Scientists repair genes in human embryos to prevent inherited diseasessteemCreated with Sketch.

in science •  7 years ago 

In a major scientific breakthrough, researchers have harnessed a gene-editing tool to correct a disease-causing gene mutation in human embryos, preventing the mutation from passing to future generations.

In the stunning discovery, a research team led by Oregon Health and Science University reported that embryos can fix themselves if scientists jump-start the process early enough.

There was no indication how soon ordinary patients could take advantage of this technique.

The new technique, which was tested on clinical-quality human eggs, uses the CRISPR-Cas9 gene-editing tool to target a mutation in nuclear DNA that causes hypertrophic cardiomyopathy, according to the researchers. Hypertrophic cardiomyopathy is a common genetic heart disease that can cause heart failure and sudden cardiac death. The disease affects approximately 1 in 500 people and is a common cause of sudden heart failure in young people, particularly young athletes.

Source: James Rogers

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