As a child all these are there inside us and life is a celebration, there is no need or want of anything external or something outside of us to complete and make us happy. Growing up sooner or later some quantity of them gets lost (reasons behind may vary) and the result is a hollowness created inside. Filling up this hollowness becomes the most important background process inside you and the search starts around the world.
You come across many things in which you find a small part of these values and the happiness is so high that you become blind and consider them to be the one you were looking for. They last temporarily with you and when they leave they leave you in agony and despair. But the search never stops.
You go on and on and on …no end to it because now a loop has started and you are so lost either into happiness of finding or in agony of losing that you never realise the existence of the loop.
You look it in substances and you abuse them until they stop fulfilling your needs, in people who become sick of your misery and leave you, in worship of gods which make you more weaker and also misguidance from stupids and insane clever ones who take advantage of you.
Also there is an inner voice inside you which tries to guide you on the correct path but its voice diminishes and gets lost and only the loop prevails.
so don't misguide yourself due to loop holes and be optimistic..