Back when I fisrt got Substance painter I did this as a really quick test to see how much work it would be to get a decent result when combined with V-Ray Renderer.
I sculpted this head really quickly in Zbrush then I used the Decimation Master and UVmaster to get something I could quickly paint in Substance. I threw it into 3ds Max with a little studio lighting setup and rendered it with V-Ray. Composited it in After Effects and used some simple color grading techniques to change the color of the paint so that I could get a sense for a lot of different styles quickly.
