illumina一间读取dna读到发达的公司

in cn •  7 years ago  (edited)

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刚刚看了王自如的"科技相对论"改变人类的基因技术,里面提到一间超厉害的公司叫illumina,心血来潮查了一下,原来illumina是一间美国的高科技公司,这公司有多厉害呢?首先,这间公司拥有全世界最便宜可以读取dna的设备,全世界90%的dna都是靠他们读取的,这可牛了,不过很多人其实并不知道读取dna是有多贵,据说在1990年,读一个人的dna需要27亿美金,到了2003年,随着科技的发展,成本降了,可是读一个人的dna还是需要5000万美金,到了2007年,成本又降了,可是读一个人的dna还是需要100万美金

而illumina所开发的机器呢?

2009年,读一个人的dna只需要48000美金
2010年,读一个人的dna只需要19500美金
2011年,读一个人的dna只需要4000美金
2014年,读一个人的dna只需要1000美金

到了2017年,他们的目标是把dna读取成本降到100美金,让每个人都可以很便宜的测试dna,可是由于全世界只有他们有这种技术,所以钱只有他们赚

那illumina这间公司值多少钱呢?

2012年, Hoffmann-La Roche 想用57亿美金买下illumina被拒绝了,到了2013年,再开价68亿美金还是被拒绝,到了2016年价值230亿美金,而且越来越贵

那其实读dna关我什么事?没有啦,我只是很想改我自己的dna所以随便研究看看现在的科技到底能不能,看来还是不行,谢谢阅读

.

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Hello Steemit friend, today I want to share a biotech company that called illumina, 90% of the world dna reading is done by them, this is how powerful they are, maybe not many people know how much does it cost to read DNA from a human, in year 1990, reading a person dan cost $2.7 billion US dollar, with the advance of technology, in year 2003, it still cost $50 million to read DNA, not until year 2007 the cost of dna reading drop to $1 million

illumina invent a machine that are able to read dna cheaper and cheaper

year 2009 - $48000
year 2010 - $19500
year 2011 - $4000
year 2014 - $1000

with this kind of technology, how much does their company worth?

during 2012, Hoffmann-La Roche offer to buy their company for $5.7 billion and being rejected, later 2013, they offer to buy the company for $6.8 billion again is being rejected, on year 2016, the company is worth $22 billion and the stock price is getting more and more expensive

thanks for reading

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  ·  7 years ago 

哈哈哈,很有想法呀。要是能改估计很多人都去改了。就看怎么改。

对啊,直接改成明星的面孔身材多好

国内的华大基因做的也不错

  ·  7 years ago (edited)

若說你想改自己的 DNA,你可以關注一下這個技術—— CRISPR/Cas9。

這是一個相當新的技術,近幾年被廣泛使用。有別於先前的鋅指與 TALEN,需要複雜的合成流程以重組蛋白質結構,CRISPR 主要藉由 RNA 模板來修改 DNA,只要針對那一序列合成專屬的 RNA 模板就行,而當中做處理的酶都可以一樣。由於其比先前更方便好用、更容易施行,這項技術在生物科技界炒得沸沸揚揚,一直都有得諾貝爾獎的呼聲。

只不過如果你想全身都做基因編輯的話,可能太遲了。你得在胚胎時期就做處理,如此一來,細胞分裂後會保有修改後的基因,整個身體才能如預期完全改動。你現在做的話也只是一個細胞 DNA 被更動而已吧!哈!哈!

对啊,都几十岁了才来改难度超大的,不知道能不能给我等到

  ·  7 years ago (edited)

幫你估算一下可能需要修改多少細胞和要花多少錢:

一個成年人會有30兆個細胞,但是,約有 84% 的細胞是紅血球,而紅血球沒有細胞核,也就是不含 DNA,我們不考慮修改這些,所以還有大約3兆個細胞需要修改。

假設我們有能力可以修改所有細胞,而且修改每顆的價格相同,那麼我們得付出:

3兆 x 修改一顆細胞定價(3000000000000 x P)

就算修改一顆只需要 0.00000333333 元,也還是得要有一百萬才行。

那我們看看世界首富比爾蓋茲若將他的所有資產都付出,把他的所有細胞作修改,修改一顆細胞的價格會是:

85600000000(856億)/ 3000000000000(3兆)= 0.02853333333

修改一顆細胞需要 0.02853333333 美金這麼便宜,才能讓一個人全身都被修改。

看起來,這真的難等啊!

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CRISPR tech is very interesting and protentional worrisome!

CRISPR技術非常有趣,潛在令人擔憂!

Your statement is right and I think it should be regulated, lest it involve a lot of public problems in the near future. Maintain the original good purpose of it.