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Throughout our lives, as we age, gene transcription "errors" accumulate in our body, replication failures, misfolded proteins, telomere wear and external epigenetic factors that deteriorate our bodies by inside and out, we call this getting old.
A lo largo de nuestra vida, a medida que vamos cumpliendo años, se acumulan en nuestro cuerpo "errores" de transcripción de los genes, fallos de replicación, proteínas mal plegadas, desgaste de los telómeros y factores epigenéticos externos que van deteriorando nuestros cuerpos por dentro y por fuera, a esto lo llamamos envejecer.
If we are capable of understanding the functioning of these biological processes and if, in some way, we could artificially stop or reverse these processes, we could stop or even reverse aging, extending the life expectancy of the human species by a few hundred years.
Si somos capaces de entender bien el funcionamiento de estos procesos biológicos y si, de alguna manera, pudiésemos artificialmente detener o revertir dichos procesos podríamos detener o incluso revertir el envejecimiento, alargando la esperanza de vida de la especie humana unos cientos de años.
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According to experts, to avoid this, cells should be "reprogrammed", that is, take these cells years ago until they become pluri-potential cells or stem cells that can later lead to any type of cell, but this seems to cause the cell to lose the function for which it was programmed.
Según los expertos para evitar esto las células deberían "reprogramarse", es decir, llevar estas células años atrás hasta convertirlas en células pluri-potenciales o células madre que pueden posteriormente derivar en cualquier tipo de célula, pero esto parece que provoca que la célula pierda la función para la que estaba programada.
What is proposed in this new theory is a transitory re-programming, or what is the same, only temporarily reprogram a specific phase of the cell, the maturation phase. This allows the biological clock of the cell to be delayed but without reaching the point of losing the intrinsic function for which it was originally designed.
Lo que se propone en esta nueva teoría es una re-programación transitoria, o lo que es lo mismo, reprogramar solo temporalmente una fase concreta de la célula, la fase de maduración. Esto permite retrasar el reloj biológico de la célula pero sin llegar al punto de perder la función intrínseca para la que estaba diseñada originalmente.
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According to the results obtained in the studies, the maturation phase transient reprogramming (MPTR), far exceeds the methods used previously, with this method it was possible to substantially rejuvenate multiple cellular attributes around 30 years, according to their methods of measuring these stuff.
Según los resultados obtenidos en los estudios la reprogramación transitoria de la fase de maduración (MPTR), supera con creces a los métodos utilizados anteriormente, con este método se consiguió rejuvenecer sustancialmente múltiples atributos celulares alrededor de 30 años, según sus métodos de medición de estas cosas.
It is true that old age brings wisdom and inner peace but it also reduces our ability to move and every day we learn more about anatomy by counting the number of bones that creak us, old age would be wonderful with the vigorous body of a 30-year-old person and maturity mind of a 200 year old.
I hope to be in time to see it.
Es cierto que la vejez aporta sabiduría y paz interior pero también reduce nuestra capacidad de movimiento y cada día sabemos más de anatomía contando el número de huesos que nos crujen, la vejez sería maravillosa con el cuerpo vigoroso de una persona de 30 años y la madurez mental de una persona de 200 años.
Espero que me dé tiempo a disfrutarlo.
More information/Más información
https://elifesciences.org/articles/71624
It seems excellent to me that they improve the technique to rejuvenate, but they also have to improve the brain of the human being, so that it is a little more human and they do not destroy this planet and we can really enjoy that technique on a healthy planet.
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Hi @mauromar the man every day approaches the dreamed day of achieving eternal youth, this would bring several implications worthy of analysis, maturity, the vital state of the organs, the time in which you live again as young socially speaking..very interesting your publication I enjoyed it and I greet you and wish you success.
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Thanks for your comment.
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Looking young in old age
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Hello @mauromar, I share with you this thought about enjoying the worst stage of maturity within a rejuvenated and vigorous body.
I am a regular reader of articles on anti-aging medicine, and what you are sharing with us today is very encouraging.
Just thinking that our cells can be reprogrammed to a specific point in time is like thinking that the undesirable process of aging would be delayed, but preserving the best results of the cellular process itself.
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